Our Past Research and Manuscripts Being Written

Learn about what we have done at
Canada East Spine Centre

Is Instrumentation Removal Required Following Minimally Invasive Percutaneous Fixation of Thoraco-Lumbar Fractures?
The objective of this study is to determine whether or not percutaneous stabilization instrumentation requires removal following fixation of traumatic thoracic or lumbar fractures. Current standard of care is instrumentation removal one year after the traumatic event.
Stability of recovery patterns following spine surgery
This study aims to investigate post-operative recovery intervals following thoracic and cervical spine surgery. Currently, the patient’s postoperative course is evaluated at 3-months, 6-months, 12-months and 2-years. Post-operative evaluations will be assessed in an effort to support the hypothesis that patient status will remain stable from 6-month follow up until one year post-op.
Presurgical utilization of physicians, imaging and injections reported by elective thoracolumbar surgery candidates: a retrospective nationwide cost-analysis from the CSORN database.
The primary objective of the current study is an initial investigation into the costs associated with the patient reported utilization seen in Canada of physician visits, imaging, injections and tests 6 months prior to Thoraco-lumbar surgical consult for 2014 and 2015, using the CSORN national database. A secondary objective for the proposed study is to elucidate if there is a significance difference in utilization based on reported levels of pain, patients’ chief complaint or province.
Nationwide quality assessment of the Canadian Spine Outcome and Research Network (CSORN)
The objective of this study is to assess the quality of the CSORN database at each of the 20 sites across Canada to determine if there are differences in data quality depending on the presence of an on-site research coordinator, mandatory data collection training, standard operating procedure, and clinical health professionals to assist with surgeon collected forms.
Elucidating the prevalence and predictors associated with spine surgery revisions at the Canada East Spine Center
The first objective of this project will be to determine the rate of revision surgeries at the Canada East Spine Centre. The second objective will be to determine if group differences in preoperative, intra-operative, or post-operative factors exist between patients who require revision surgery and those who do not. We will be examining factors intrinsic to the patient, the surgery itself, as well as the surgeon. The third objective, if statistically feasible, will be to attempt to elucidate any factors that may predict the need for future revision surgery in new patients.
Same Day Readmission Following Outpatient Lumbar Spine Surgery
Determine the prevalence of same day readmittance and provide descriptive analysis of the reasons for readmittance. Determine if there are any significant demographic or surgical group difference between patients who are readmitted compared to those who are not, and depending on results of group differences and sample size achieved. Investigate if there is a predictive model for readmission.
Patient-Reported disability vs.
Objective Physical Performance
Measures in Assessing
Patient Recovery
This is a collaborative project between Drs. Manson and Abraham and Dr. Wayne Albert of the UNB Kinesiology department. In this study, we aimed to compare objective measures of biomechanical ability to patient-reported pain and disability. The manuscript is currently in preparation.
Latent Trajectory Growth Analysis: Modelling Patient Recovery to Predict Two-Year Outcomes Following Elective Thoracolumbar Surgery for
Degenerative Pathologies
This was a collaboration between Dr. Manson, Dr. Abraham and Josh Murray, a Horizon Health Network Biostatistician. We paired up with Josh to figure out the best way to understand and quantify our patients’ post-operative recovery. With Josh’s extensive training in biostatistics, he helped write a program that assessed patterns of recovery up to two years after surgery. This study gave us a better understanding of patients’ postoperative experience and preoperative factors that may help predict that. Manuscript in preparation!
Decompression with and Interspinous Process Device vs. Decompression and Fusion for the Treatment of Stable Degenerative Spondylolisthesis
Decompression with an Interspinous Process Device (DIPD) is a relatively new, motion-sparing technique. This study compared two-year outcomes of patients who received a DIPD to those receiving a traditional decompression and fusion technique. Manuscript in preparation. Stay tuned for publication information!
Opioid Analgesic Use in Patients with Degenerative Thoracolumbar Spine Pathologies: Impact of Surgical Intervention and Predictors of Long-Term Use
This is a retrospective analysis of our CESC database, in collaboration with Dr. Caroline Brunelle and her thesis student Scott Lilly. Caroline brought her expertise in opioid analgesic addictions to the table to take an in-depth look at chronic postoperative opioid use in our spine patient population. This manuscript is in preparation.
Does Selective Nerve Root Injection Prevent the Need for Surgery in Patients with Sciatica Secondary to Lumbar
Disc Herniation?

This is a two-step project aiming to assess whether guided nerve root injections help patients avoid the need for spine surgery following disc herniation. The first stage was completed in 2008 and recently published

We are finished the second phase of this project - a prospective randomized placebo-controlled double-blind Health Canada-monitored study.

Post-Operative Ambulation in Patients Undergoing Total Hip Arthroplasty,
Total Knee Arthroplasty and Lumbar Fusion for
Arthritic Pathologies
This is a prospective study initiated by Dr. Connolly, Dr. Abraham and Dr. Manson in collaboration with medical student Mike Cochran and the nursing and physio staff on the Orthopaedics floor. We are aiming to compare post-operative walking between hip, knee and spine surgery patients, in order to create quantitative guidelines for safe hospital discharge. The manuscript is currently being prepared for publication. Many thanks to the Health Innovation Research Fund and APOS for supporting this study.